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Unveiling the oncogenic significance of thymidylate synthase in human cancers

1 Jan 2024

Abstract excerpt

OBJECTIVE: Thymidylate synthase (TYMS) constitutes a pivotal and potent target in the context of chemoresistance. However, the oncogenic role of TYMS has received insufficient attention. METHODS: Leveraging data from the Cancer Genome Atlas (TCGA) and various public databases, we conducted an extensive investigation into the oncogenic role of TYMS across 33 cancer types. Subsequently, TYMS was inhibited using...

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PMID: 39544745
DOI: 10.62347/iruz1011

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