Article

Somatic BRCA Mutation in Cholangiocarcinoma Patient Utilized to Individualize an HBOC Syndrome

2019-11-17

Abstract excerpt

BRCA-associated hereditary breast and ovarian cancer syndrome (HBOC) implies increased absolute risk also for other malignancies such as cholangiocarcinoma (CCA). However, even if somatic mutations in CCA have been reported, there are no data on its utilization as predisposing genetic factor in a family. For the first time, we utilized CCA somatic BRCA mutation to individualize a family with HBOC. A 47-year-old wo...

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Literature Corpus work: c9f990f1-6ea2-5b90-857e-b54b67d8d79d
DOI: 10.20944/preprints201911.0200.v1

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