Article
Using the Icelandic genealogical database to define the familial risk of primary biliary cholangitis.
Hepatology (Baltimore, Md.) - 1 Jul 2018
Örnolfsson Kristjan T, Olafsson Sigurdur, Bergmann Ottar M, Gershwin M Eric, Björnsson Einar S
Abstract excerpt
Hereditary factors in primary biliary cholangitis (PBC) have been well defined in genome-wide association studies, but there are few direct data available that define the relative risk (RR) for family members with an affected proband. An increased risk in first-degree relatives has been demonstrated in a variety of studies, but data have been lacking on further detailed associations for subsequent generations....
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