Article

A pathogenic germline BRCA1 mutation in a patient with non-Hodgkin lymphoma and rectum adenocarcinoma

2023-02-28

Abstract excerpt

Tumor suppressor gene BRCA1, known for its vital roles in regulating DNA damage, is frequently mutated in hereditary breast and ovarian cancer (HBOC), whose mutation also increases susceptibility to intestinal, prostatic and pancreatic cancers of patients. As the main subtype of lymphoma, non-Hodgkin lymphoma (NHL) is malignant disorders arising from immune cells and displays predominantly as lymphadenopathy or so...

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Literature Corpus work: 4a56f3f2-0349-5957-8004-5cefe0e37ce0
DOI: 10.21203/rs.3.rs-2622517/v1

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