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Article

A case of unresectable intrahepatic cholangiocarcinoma with a germline BRCA1 mutation.

Clinical journal of gastroenterology - 1 Jun 2023

Yamashita Yumiko, Ishii Yasutaka, Serikawa Masahiro, Okamoto Wataru, Tsuboi Tomofumi, Tatsukawa Yumiko, Nakamura Shinya, Hirano Tetsuro, Ikemoto Juri, Oka Shiro

Abstract excerpt

Intrahepatic cholangiocarcinoma (ICC) is a malignant liver tumor with poor prognosis. Various mutations in cancer-predisposing genes have been reported in ICC, and germline BRCA1/2 mutations, which are the causative genes for hereditary breast and ovarian cancer syndrome (HBOC), have been reported in many patients with ICC. Here, we report a case of unresectable ICC with a germline BRCA1 mutation. A 73-year-old...

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PMID: 36806982
DOI: 10.1007/s12328-023-01772-3

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