Article

Unexpected finding of a rare pathogenic germline BRCA1 variant in an intrahepatic cholangiocarcinoma using the Oncomine Focus DNA assay: clinical and diagnostic implications

2023-05-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Cholangiocarcinoma (CCA) is a malignant tumor arising from the epithelial cells of the bile ducts and is the second most common liver cancer after hepatocellular carcinoma. Recently, our Institution launched a Comprehensive Genomic Profiling (CGP) program (named FPG500 program), set up to provide a complete molecular characterization through the TruSight Oncology...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1763d0ce-2f3e-53ea-8fbb-e88dd160e700
DOI: 10.21203/rs.3.rs-2880020/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Unexpected finding of a rare pathogenic germline BRCA1 variant in an intrahepatic cholangiocarcinoma using the Oncomine Focus DNA assay: clinical and diagnostic implicationsDOI 10.21203/rs.3.rs-2880020/v1Read

Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic informationSemantic proximity Read

Practical guidelines for molecular testing of cholangiocarcinoma in clinical practice: Italian experts’ position paperSemantic proximity Read

Current challenges to underpinning the genetic basis for cholangiocarcinoma.Semantic proximity Read

Update on cholangiocarcinoma: potential impact of genomic studies on clinical management.Semantic proximity Read

Comprehensive Analysis of Genomic Mutation Signature and Tumor Mutation Burden for Prognosis of Intrahepatic CholangiocarcinomaSemantic proximity Read

Intrahepatic Cholangiocarcinoma: Genomic Heterogeneity Between Eastern and Western PatientsSemantic proximity Read

Mutational Landscape of Cholangiocarcinoma According to Different Etiologies: A Review.Semantic proximity Read

Molecular Testing for Intrahepatic Cholangiocarcinoma: What, When, How?Semantic proximity Read

Overall Survival and Clinical Characteristics of BRCA-Associated Cholangiocarcinoma: A Multicenter Retrospective Study.Semantic proximity Read

Somatic BRCA Mutation in Cholangiocarcinoma Patient Utilized to Individualize an HBOC SyndromeSemantic proximity Read

Genomic feature and potential therapeutic target for cholangiocarcinomaSemantic proximity Read

Untitled literature recordSemantic proximity Read