Back to search

Article

Molecular Mechanisms of Iron Metabolism and Overload in Sickle Cell Disease

2025-02-12

Abstract excerpt

Iron represents a vital element needed for normal physiologic functions across the body. A vast network of transporters is involved not only in uptake but in processing, oxidation and recycling to maintain this element in a tight balance to avoid excess storage. This complex network of transporters including heme and ferroportin among many others are responsible for facilitating inter-organ and tissue iron exchang...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c9b5771f-31dc-59ec-a89b-c5aef5693b6a
DOI
10.20944/preprints202502.0957.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Molecular Mechanisms of Iron Metabolism and Overload in Sickle Cell DiseaseDOI 10.20944/preprints202502.0957.v1
Ferroptosis as an emerging target in sickle cell diseaseSemantic proximity
Iron Homeostasis in Health and DiseaseSemantic proximity
Crosstalk Between Sickle Cell Disease and FerroptosisSemantic proximity
Iron Metabolism in Normal and Pathological Pregnancies and Fetal ConsequencesSemantic proximity
Iron Metabolism in Thalassemia and Sickle Cell Anemia: The influence of Genetic ModifiersSemantic proximity
Iron metabolism: iron deficiency and iron overload.Semantic proximity
Molecular and clinical aspects of iron homeostasis: From anemia to hemochromatosis.Semantic proximity
Intracellular Iron Transport and Storage: From Molecular Mechanisms to Health ImplicationsSemantic proximity
The regulation of cellular iron metabolism.Semantic proximity
Consequences and management of iron overload in sickle cell diseaseSemantic proximity
Iron homeostasis and inherited iron overload disorders: an overviewSemantic proximity
Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical ManagementSemantic proximity
Select a neighboring publication to make it the new centre.