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Iron Metabolism in Thalassemia and Sickle Cell Anemia: The influence of Genetic Modifiers

2024-07-02

Abstract excerpt

Iron metabolism plays a crucial role in the management of hemoglobinopathies, particularly in conditions such as β-thalassemia and sickle cell anemia (SCA). This paper describes the mechanisms of iron overload in patients with transfusion-dependent thalassemia (TDT), non-transfusion-dependent thalassemia (NTDT), and SCA, highlighting the distinct paths leading to iron accumulation in each condition. The primary fo...

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Literature Corpus work
a985e59a-c2dc-5428-9616-5ba84092b607
DOI
10.20944/preprints202407.0167.v1
Open publication

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