Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Iron metabolism: iron deficiency and iron overload.

Annual review of genomics and human genetics - 1 Jan 2000

Andrews N C

Abstract excerpt

Iron is an essential cofactor in a variety of cellular processes. Except for a few unusual bacterial species, iron is indispensable for living organisms. However, free iron is toxic because of its propensity to induce the formation of dangerous free radicals. Consequently, iron balance is tightly regulated. Disorders of iron homeostasis are among the most common afflictions of humans. This review discusses...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Iron-Deficiency
Share to Anemia, Sideroblastic
Share to Intestinal Absorption

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Iron Deficiencies

Share to Iron Metabolism Disorders

Share to Iron Overload

Share to Transferrin

Source

Identifiers

PMID: 11701625
DOI: 10.1146/annurev.genom.1.1.75

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Iron metabolism: iron deficiency and iron overload.PMID 11701625Read ↗

Iron homeostasis and inherited iron overload disorders: an overviewSemantic proximity Read ↗

Iron Homeostasis in Health and DiseaseSemantic proximity Read ↗

Molecular and clinical aspects of iron homeostasis: From anemia to hemochromatosis.Semantic proximity Read ↗

Iron homeostasis: new players, newer insightsSemantic proximity Read ↗

Dysregulated Iron Homeostasis as Common Disease Etiology and Promising Therapeutic TargetSemantic proximity Read ↗

Review article: the iron overload syndromes.Semantic proximity Read ↗

Rare causes of hereditary iron overload.Semantic proximity Read ↗

Iron, Copper, and Zinc Homeostasis: Physiology, Physiopathology, and Nanomediated ApplicationsSemantic proximity Read ↗

Molecular Mechanisms of Iron and Heme MetabolismSemantic proximity Read ↗

Iron TransportSemantic proximity Read ↗

Iron homeostasis: transport, metabolism, and regulation.Semantic proximity Read ↗

Managing the Dual Nature of Iron to Preserve HealthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.