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Article

Consequences and management of iron overload in sickle cell disease

6 Dec 2013

Abstract excerpt

The aims of this review are to highlight the mechanisms and consequences of iron distribution that are most relevant to transfused sickle cell disease (SCD) patients and to address the particular challenges in the monitoring and treatment of iron overload. In contrast to many inherited anemias, in SCD, iron overload does not occur without blood transfusion. The rate of iron loading in SCD depends on the blood...

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PMID: 24319218
DOI: 10.1182/asheducation-2013.1.447

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