Identification of Blood Biomarkers for Alzheimer's Disease Through Computational Prediction and Experimental Validation

Abstract excerpt

Background: Alzheimer’s disease (AD) is the major cause of dementia in population aged over 65 years, accounting up to 70% dementia cases. However, validated peripheral biomarkers for AD diagnosis are not available up to present. In this study, we adopted a new strategy of combination of computational prediction and experimental validation to identify blood protein biomarkers for AD. Methods: First, we collected...

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