Article

All-optical electrophysiology in hiPSC-derived neurons with synthetic voltage sensors

2021-01-19

Abstract excerpt

Voltage imaging and “all-optical electrophysiology” in human induced pluripotent stem cell (hiPSC)-derived neurons have opened unprecedented opportunities for high-throughput phenotyping of activity in neurons possessing unique genetic backgrounds of individual patients. While prior all-optical electrophysiology studies relied on genetically encoded voltage indicators, viral transduction of human neurons with larg...

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Literature Corpus work: c974efce-d00f-5710-afeb-b5e4c33b161c
DOI: 10.1101/2021.01.18.427081

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