Article

Pancreatic Cancer Intrinsic PI3Kα Activity accelerates Metastasis and rewires Macrophage Component

2020-09-24

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) patients frequently suffer from undetected micrometastatic disease. This clinical situation would greatly benefit from additional investigation. Therefore, we set out to identify key signalling events that drive metastatic evolution from the pancreas. We researched a gene signature that could discriminate localised PDAC from confirmed metastatic PDAC and devised a preclinica...

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Identifiers and source

Literature Corpus work: c942c647-cd31-56bf-b4fe-b16e4599e75a
DOI: 10.1101/2020.09.23.307884

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