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Article

Opportunities and Resistance to Signal-targeted Therapies in Pancreatic Cancer: What Can We Learn from Proteomic Studies?

2018-02-01

Abstract excerpt

In metastatic pancreatic cancer patients non eligible to surgery, signal-targeted therapies so far failed to show a significant amelioration of survival. These therapeutic options were tested in Phase II/III clinical trials mostly in combination with the reference treatment Gemcitabine. These innovative therapies aim at annihilating the oncogene dependency; they also aim at renormalizing the tumoral stroma to allo...

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Literature Corpus work
4a6ca749-f6e1-583d-8614-3095782dc4e1
DOI
10.20944/preprints201802.0011.v1
Open publication

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