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Article

p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation.

World journal of gastroenterology - 7 Sept 2018

Wang Kai, Baldwin Graham S, Nikfarjam Mehrdad, He Hong

Abstract excerpt

Pancreatic cancer is one of the most aggressive and lethal malignancies worldwide, with a very poor prognosis and a five-year survival rate less than 8%. This dismal outcome is largely due to delayed diagnosis, early distant dissemination and resistance to conventional chemo-therapies. Kras mutation is a well-defined hallmark of pancreatic cancer, with over 95% of cases harbouring Kras mutations that give rise to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30197477
DOI: 10.3748/wjg.v24.i33.3709
PMCID: PMC6127653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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