Article

Study of the toxicity, immunological and gene expression effects of cobalt ions and wear debris derived from metal-on-metal hip implants

2013-01-01

Abstract excerpt

Joint replacements have been used for over 30 years with considerable success as treatment for bone diseases. As a surgical alternative to metal on metal (MoM) total hip replacement, hip resurfacing was developed using Cobalt-Chromium (CoCr) alloys. However, debris particles are generated by wear at the articulating CoCr surfaces. The nanoparticles and ions produced disseminate throughout the body and interact wit...

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Literature Corpus work: c93ae124-3c9f-514d-8271-f317e02d0991
DOI: 10.48730/p086-qq32

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