Article
Albumin as marker for susceptibility to metal ions in metal-on-metal hip prosthesis patients.
Human & experimental toxicology - 1 Apr 2017
Facchin F, Catalani S, Bianconi E, Pasquale D De, Stea S, Toni A, Canaider S, Beraudi A
Abstract excerpt
Metal-on-metal (MoM) hip prostheses are known to release chromium and cobalt (Co), which negatively affect the health status, leading to prosthesis explant. Albumin (ALB) is the main serum protein-binding divalent transition metals. Its binding capacity can be affected by gene mutations or modification of the protein N-terminal region, giving the ischaemia-modified albumin (IMA). This study evaluated ALB, at gene...
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