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Biological insights from the whole genome analysis of human embryonic stem cells

2020-10-26

Abstract excerpt

<h4>ABSTRACT</h4> There has not yet been a systematic analysis of hESC whole genomes at a single nucleotide resolution. We therefore performed whole genome sequencing (WGS) of 143 hESC lines and annotated their single nucleotide and structural genetic variants. We found that while a substantial fraction of hESC lines contained large deleterious structural variants, finer scale structural and single nucleotide var...

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Literature Corpus work
c90318b0-3313-5337-8c93-eacf86ba8ce7
DOI
10.1101/2020.10.26.337352
Open publication

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Biological insights from the whole genome analysis of human embryonic stem cellsDOI 10.1101/2020.10.26.337352
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