Article
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC biology - 18 Aug 2006
Josephson Richard, Sykes Gregory, Liu Ying, Ording Carol, Xu Weining, Zeng Xianmin, Shin Soojung, Loring Jeanne, Maitra Anirban, Rao Mahendra S, Auerbach Jonathan M
Abstract excerpt
BACKGROUND: Human embryonic stem cells (hESC) offer a renewable source of a wide range of cell types for use in research and cell-based therapies to treat disease. Inspection of protein markers provides important information about the current state of the cells and data for subsequent manipulations. However, hESC must be routinely analyzed at the genomic level to guard against deleterious changes during extensive...
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