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Article

Human Stem Cell Resources Are an Inroad to Neandertal DNA Functions.

Stem cell reports - 14 Jul 2020

Dannemann Michael, He Zhisong, Heide Christian, Vernot Benjamin, Sidow Leila, Kanton Sabina, Weigert Anne, Treutlein Barbara, Pääbo Svante, Kelso Janet, Camp J Gray

Abstract excerpt

Induced pluripotent stem cells (iPSCs) from diverse humans offer the potential to study human functional variation in controlled culture environments. A portion of this variation originates from an ancient admixture between modern humans and Neandertals, which introduced alleles that left a phenotypic legacy on individual humans today. Here, we show that a large iPSC repository harbors extensive Neandertal DNA,...

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Identifiers

PMID: 32559457
DOI: 10.1016/j.stemcr.2020.05.018
PMCID: PMC7363959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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