Article

A needle in a haystack: metagenomic DNA sequencing to quantify <i>Mycobacterium tuberculosis</i> DNA and diagnose tuberculosis

2022-04-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Tuberculosis (TB) remains a significant cause of mortality worldwide. Metagenomic next-generation sequencing has the potential to reveal biomarkers of active disease, identify coinfection, and improve detection for sputum-scarce or culture-negative cases. <h4>Methods</h4> We conducted a large-scale comparative study of 427 plasma, urine, and oral swab samples from 334 individu...

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Literature Corpus work: ceab0ed8-d386-5458-8107-aa199013931a
DOI: 10.1101/2022.04.15.22273912

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