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Towards Culture-Free Sequencing of <i>Mycobacterium tuberculosis</i> : Evaluating New Targeted and Whole-Genome Approaches for Genotyping and Drug Resistance Profiling

2026-01-20

Abstract excerpt

<h4>Background</h4> The effectiveness of current drug-resistant tuberculosis (DR-TB) regimens is limited by the absence of rapid diagnostics that comprehensively predict resistance to included drugs. Next-generation sequencing (NGS), through culture-free targeted sequencing (tNGS) and culture-based whole-genome sequencing (cWGS) of the Mycobacterium tuberculosis complex (MTBC), offers a powerful framework for pr...

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Literature Corpus work
4d2bc06d-ee1b-519e-b707-ddf8cef3b582
DOI
10.64898/2026.01.15.26344185
Open publication

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Towards Culture-Free Sequencing of <i>Mycobacterium tuberculosis</i> : Evaluating New Targeted and Whole-Genome Approaches for Genotyping and Drug Resistance ProfilingDOI 10.64898/2026.01.15.26344185
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