Article

Gene amplification during differentiation of mesenchymal stem cells towards chondrocytes

2026-06-16

Abstract excerpt

For decades gene amplifications were described as an attribute of tumor cells and as a physiological mechanism to increase gene copy numbers for the higher protein demand during development of amphibians and flies. An increasing number of publications describe gene amplifications in normal mammalian cells during differentiation. Many amplified genes detected in tumor cells overlap with amplified genes detected dur...

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Literature Corpus work: c8c1aec7-b870-5548-b2ce-9688ea883d67
DOI: 10.64898/2026.06.16.732523

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