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Genome-wide array comparative genomic hybridization analysis reveals distinct amplifications in osteosarcoma

7 Aug 2004

Abstract excerpt

BACKGROUND: Osteosarcoma is a highly malignant bone neoplasm of children and young adults. It is characterized by extremely complex karyotypes and high frequency of chromosomal amplifications. Currently, only the histological response (degree of necrosis) to therapy represent gold standard for predicting the outcome in a patient with non-metastatic osteosarcoma at the time of definitive surgery. Patients with...

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Share to Bone Tumor Diagnosis and Treatments
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15298715
DOI: 10.1186/1471-2407-4-45

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