Article

Tissue-Specific and Interorgan Metabolic Reprogramming Maintains Tolerance to Sepsis

2022-10-08

Abstract excerpt

<h4>Summary</h4> Reprogramming metabolism is of great therapeutic interest for reducing morbidity and mortality during sepsis-induced critical illness 1 . Disappointing results from randomized controlled trials targeting glutamine and antioxidant metabolism in patients with sepsis have begged for both identification of new metabolic targets, and a deeper understanding of the metabolic fate of glutamine at the sy...

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Literature Corpus work: c8b3a8af-e644-509f-b556-7937a221242a
DOI: 10.1101/2022.10.08.511411

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