Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?

5 Jul 2018

Abstract excerpt

Sepsis is a highly lethal and urgent unmet medical need. It is the result of a complex interplay of several pathways, including inflammation, immune activation, hypoxia, and metabolic reprogramming. Specifically, the regulation and the impact of the latter have become better understood in which the highly catabolic status during sepsis and its similarity with starvation responses appear to be essential in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Hyperglycemia and glycemic control in critically ill and hospitalized patients
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29976786
DOI: 10.15252/emmm.201708712

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?PMID 29976786Read ↗

Physiologic disruption and metabolic reprogramming in infection and sepsisSemantic proximity Read ↗

Metabolic reprogramming and tolerance during sepsis-induced AKISemantic proximity Read ↗

Impaired peripheral mononuclear cell metabolism in patients at risk of developing sepsis: A cohort studySemantic proximity Read ↗

Patient Stratification in Sepsis: Using Metabolomics to Detect Clinical Phenotypes, Sub-Phenotypes and Therapeutic ResponseSemantic proximity Read ↗

Metabolic Reprogramming and Host Tolerance: A Novel Concept to Understand Sepsis-Associated AKISemantic proximity Read ↗

Tissue-Specific and Interorgan Metabolic Reprogramming Maintains Tolerance to SepsisSemantic proximity Read ↗

Epigenetic and metabolic programming of innate immunity in sepsisSemantic proximity Read ↗

A New Strategy for Targeting UCP2 to Modulate Glycolytic Reprogramming as a Treatment for Sepsis A New Strategy for Targeting UCP2Semantic proximity Read ↗

Lactate and Lactylation in Sepsis: A Comprehensive ReviewSemantic proximity Read ↗

Metabolic Profiles of Critical Care Patients to Confirm Sepsis and Further Understand the Metabolic Phenotype of Sepsis.Semantic proximity Read ↗

Epigenetic Modulation by Lactylation in Sepsis: Linking Metabolism to Immune DysfunctionSemantic proximity Read ↗

The Overlapping Biology of Sepsis and Cancer and Therapeutic ImplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.