Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sepsis Induces Long‐Term Muscle and Mitochondrial Dysfunction due to Autophagy Disruption Amenable by Urolithin A

1 Aug 2025

Abstract excerpt

ABSTRACT Background Sepsis survivors often experience sustained muscle weakness, leading to physical disability, with no pharmacological treatments available. Despite these well‐documented long‐term clinical consequences, research exploring the cellular and molecular mechanisms is sorely lacking. Methods Bioinformatic analysis was performed in the vastus lateralis transcriptome of human ICU survivors 7 days after...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Nutrition and Health in Aging
Share to Protease and Inhibitor Mechanisms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40817441
DOI: 10.1002/jcsm.70041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sepsis Induces Long‐Term Muscle and Mitochondrial Dysfunction due to Autophagy Disruption Amenable by Urolithin APMID 40817441Read ↗

Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survivalSemantic proximity Read ↗

Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injurySemantic proximity Read ↗

Beyond the Pump: Unravelling Immunometabolic Crosstalk and Organelle Dynamics in Sepsis-Induced Cardiomyopathy.Semantic proximity Read ↗

Glycogen Synthase Kinase-3β Inhibitor Lithium Chloride Protects Against Inflammation-Mediated Skeletal Muscle WastingSemantic proximity Read ↗

Multidimensional Landscape of SA-AKI Revealed by Integrated Proteomics and Metabolomics AnalysisSemantic proximity Read ↗

Sepsis-Associated Muscle Wasting: A Comprehensive Review from Bench to BedsideSemantic proximity Read ↗

Identification of ferroptosis-related genes in male mice with sepsis-induced acute lung injury based on transcriptome sequencingSemantic proximity Read ↗

Rel+ macrophages disturbing cardiac niche contributes to cardiac dysfunction following sepsis.Semantic proximity Read ↗

The Role of Autophagy in Sepsis: Protection and Injury to OrgansSemantic proximity Read ↗

Mechanism of Mitophagy and Its Role in Sepsis Induced Organ Dysfunction: A ReviewSemantic proximity Read ↗

The possible mechanisms of ferroptosis in sepsis-associated acquired weaknessSemantic proximity Read ↗

Tissue-Specific and Interorgan Metabolic Reprogramming Maintains Tolerance to SepsisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.