Article

Parkinson’s disease-associated alterations in DNA methylation and hydroxymethylation in human brain

2024-05-22

Abstract excerpt

Epigenetic mechanisms are mediators of interactions between aging, genetics, and environmental factors in sporadic Parkinson’s disease (PD). Multiple studies have explored the DNA modifications in PD, but few focus on 5-hydroxymethylcytosine (5-hmC), which is important in the central nervous system and sensitive to environmental exposures. To date, studies have not differentiated between 5-methylcytosine (5-mC) an...

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Literature Corpus work: c8b05e52-d5fc-5236-a22a-d2ad1788f4c8
DOI: 10.1101/2024.05.21.595193

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