Article

Clostridium difficile exploits a host metabolite produced during toxin-mediated infection

2021-01-15

Abstract excerpt

Several enteric pathogens can gain specific metabolic advantages over other members of the microbiota by inducing host pathology and inflammation. The pathogen Clostridium difficile ( Cd ) is responsible for a toxin-mediated colitis that causes 15,000 deaths in the U.S. yearly 1 , yet the molecular mechanisms by which Cd benefits from toxin-induced colitis remain understudied. Up to 21% of healthy adults are a...

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Literature Corpus work: c8a3d11b-24d4-5f7a-9f8a-7825dd2e28ad
DOI: 10.1101/2021.01.14.426744

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