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Article

C. difficile exploits a host metabolite produced during toxin-mediated disease.

Nature - 1 May 2021

Pruss Kali M, Sonnenburg Justin L

Abstract excerpt

Several enteric pathogens can gain specific metabolic advantages over other members of the microbiota by inducing host pathology and inflammation. The pathogen Clostridium difficile is responsible for a toxin-mediated colitis that causes 450,000 infections and 15,000 deaths in the United States each year1; however, the molecular mechanisms by which C. difficile benefits from this pathology remain unclear. To...

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Share to Gene Expression Regulation, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33911281
DOI: 10.1038/s41586-021-03502-6
PMCID: PMC9067157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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