Article
Exploring the methylome and transcriptome of young adult and aged OPCs
2018-01-01
Abstract excerpt
Remyelination is the restoration of myelin sheaths to denuded axons following demyelinating events, which occurs spontaneously in adult mammals, including humans. The principal cells which participate in remyelination are the Oligodendrocyte Progenitor Cells (OPCs). Similar to other regenerative processes, remyelination efficiency declines with ageing. It is still unknown how much of this decline can be attributed...
Topics
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- Adipose Tissue and Metabolism
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Multiple Sclerosis Research Studies
- Neurogenesis and neuroplasticity mechanisms
- Neurogenetic and Muscular Disorders Research
- Neuroinflammation and Neurodegeneration Mechanisms
Identifiers and source
- Literature Corpus work
- c875c2b9-7d8d-55e0-ae40-5e0ac6fb4de0
- DOI
- 10.17863/cam.20370
