Article

Inhibition of Tgfβ signaling enables durable ventricular pacing by TBX18 gene transfer

2022-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Implantable cardiac pacemaker devices are generally effective for patients with symptomatic bradyarrhythmia. However, device-dependent cardiac pacing is far from ideal and often inadequate, particularly for pediatric patients who need to go through invasive revision of the indwelling hardware. Biological pacemakers have been proposed as device-free alternatives to the current treatment, but sust...

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Literature Corpus work: c8462c22-065e-5d87-97af-03226aa29867
DOI: 10.1101/2022.06.02.493572

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