Article

Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells

2022-02-22

Abstract excerpt

<h4>ABSTRACT</h4> Inositol plays a significant role in cellular function and signaling. Studies in yeast have demonstrated an “inositol-less death” phenotype, suggesting that inositol is an essential metabolite. In yeast, inositol synthesis is highly regulated, and inositol levels have been shown to be a major metabolic regulator, with its abundance affecting the expression of hundreds of genes. Abnormalities in...

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Literature Corpus work: c810c6cd-5605-52af-9f36-d8256e77bd93
DOI: 10.1101/2022.02.21.481362

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