Article
Modeling the Resilience of Neural Topologies: A Computational Approach to Understanding Cognitive Reserve in Alzheimer's Disease
2024-12-09
Abstract excerpt
The concept of cognitive reserve has emerged as a critical framework in understanding resilience to neurodegenerative diseases like Alzheimer’s. Cognitive reserve hypothesises that individuals with more complex neural networks can delay the onset of disease symptoms due to the robustness of their neural architecture. To test this theory, we developed a computational model that simulates progressive neuronal...
Topics
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- Advanced Neuroimaging Techniques and Applications
- Alzheimer's disease research and treatments
- Functional Brain Connectivity Studies
- Genetics, Aging, and Longevity in Model Organisms
- Mitochondrial Function and Pathology
- Neurogenesis and neuroplasticity mechanisms
- Neuroscience and Neuropharmacology Research
- Nuclear Receptors and Signaling
Identifiers and source
- Literature Corpus work
- c7ed4161-4ed9-555e-81a2-acc459578c24
- DOI
- 10.20944/preprints202412.0693.v1
