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Synaptic resilience is associated with maintained cognition during ageing

2022-05-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> It remains unclear why age increases risk of Alzheimer’s disease and why some people experience age-related cognitive decline in the absence of dementia. Here we test the hypothesis that resilience to molecular changes in synapses contribute to healthy cognitive ageing. <h4>METHODS</h4> We examined post-mortem brain from people in mid-life (n=15), healthy ageing with...

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Literature Corpus work
b9361e9a-fa95-564c-9ffa-7d4ffde06905
DOI
10.1101/2022.05.04.22274679
Open publication

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Synaptic resilience is associated with maintained cognition during ageingDOI 10.1101/2022.05.04.22274679
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