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Article

Systemic lupus erythematosus-accelerated atherosclerosis: mechanistic insights and clinical implications.

Frontiers in immunology - 1 Jan 2026

Li Dexiu, Ma Dongyue, Zheng Liying, Zhao Lin, Qiu Ziyi, Xue Mei

Abstract excerpt

Premature coronary atherosclerosis remains a primary driver of late-stage mortality in systemic lupus erythematosus (SLE), independent of traditional cardiovascular risk profiles. This mini-review outlines the multifaceted immunometabolic pathways that underpin accelerated atherogenesis in SLE patients. We examine how chronic systemic inflammation modifies the lipoprotein profile toward a pro-oxidant state,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42099601
DOI: 10.3389/fimmu.2026.1818480
PMCID: PMC13143929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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