Article

Picrorhiza II inhibits the progress of HNSCC tumors by reducing the expression of MARK4 in tumor cells to hinder macrophage infiltration and polarization

2026-05-26

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> The majority of HNSCC patients respond very poorly to first-line clinical treatment. The main reasons for this are the lack of sensitive biomarkers and the lack of effective drug candidates. <bold>Results</bold> We discovered that HNSCC tumors have the ability to evade the immune system by employing a particular cellular protein, namely MARK4. MARK4 facilita...

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Literature Corpus work: c7d2deca-fe73-59e0-8e50-f0d82bb62bd5
DOI: 10.21203/rs.3.rs-9643850/v1

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