Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HYR-2 plays an anti-lung cancer role by regulating PD-L1 and Akkermansia muciniphila.

Pharmacological research - 1 Oct 2020

Teng Linxin, Wang Kaiyuan, Chen Weiping, Wang Yun-Shan, Bi Lei

Abstract excerpt

Traditional Chinese medicine (TCM) plays a vital part in cancer treatment due to its unique superiority. Huoxue Yiqi Recipe-2 (HYR-2) was supposed to have therapeutic effect on lung cancer, which came from Ze Qi Decoction in one of the four great classics of TCM called "Synopsis of Prescriptions of the Golden Chamber". Network pharmacology demonstrated that the targets of active components from HYR-2 were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to A549 Cells
Share to B7-H1 Antigen
Share to Drugs, Chinese Herbal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hep G2 Cells

Share to Immune Checkpoint Inhibitors

Share to MCF-7 Cells

Share to Medicine, Chinese Traditional

Share to Tumor Burden

Source

Identifiers

PMID: 32687951
DOI: 10.1016/j.phrs.2020.105086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HYR-2 plays an anti-lung cancer role by regulating PD-L1 and Akkermansia muciniphila.PMID 32687951Read ↗

Molecular mechanism of the anti-lung cancer effect of Jin Ning Fang based on network pharmacology and experimental verificationSemantic proximity Read ↗

Combining network pharmacology and transcriptomics to validate and explore the efficacy and mechanism of Huayu Wan in treating non-small cell lung cancerSemantic proximity Read ↗

Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancerSemantic proximity Read ↗

Network Pharmacology and Experiment Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma RecurrenceSemantic proximity Read ↗

The SARS-CoV-2 host cell membrane fusion protein TMPRSS2 is a tumor suppressor and its downregulation correlates with increased antitumor immunity and immunotherapy response in lung adenocarcinomaSemantic proximity Read ↗

Corynoxine suppresses lung adenocarcinoma proliferation and metastasis via inhibiting PI3K/AKT pathway and suppressing Cyclooxygenase-2 expressionSemantic proximity Read ↗

Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancerSemantic proximity Read ↗

PYCR1 knockdown inhibits the proliferation, migration, and invasion by affecting JAK/STAT signaling pathway in lung adenocarcinomaSemantic proximity Read ↗

Molecular targets and mechanisms of cortex mori for lung cancer treatment: A network pharmacology study, molecular docking and experimental validationSemantic proximity Read ↗

Herbal formula Yangyinjiedu induces lung cancer cell apoptosis via activation of early growth response 1Semantic proximity Read ↗

A Network Pharmacology Approach to Investigating the Mechanism of Sophorae Flavescentis Radix for the Treatment of Lung CancerSemantic proximity Read ↗

Elaiophylin Inhibits Tumorigenesis of Human Lung Adenocarcinoma by Inhibiting Mitophagy via Suppression of SIRT1/Nrf2 SignalingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.