Article

P311 induces a TGF-β1–independent, nonfibrogenic myofibroblast phenotype

2002-11-01

Abstract excerpt

P311, also called PTZ17, was identified by suppressive subtraction hybridization as potentially involved in smooth muscle (SM) myogenesis. P311 is an 8-kDa protein with several PEST-like motifs found in neurons and muscle. P311 transfection into two fibroblast cell lines, NIH 3T3 and C3H10 T1/2, induced phenotypic changes consistent with myofibroblast transformation, including upregulation of SM α−actin and SM22,...

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Literature Corpus work: c7acd5d4-069e-542a-ac41-e86ee40e9968
DOI: 10.1172/jci0215614

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