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Article

Smad2 and PEA3 cooperatively regulate transcription of response gene to complement 32 in TGF-β-induced smooth muscle cell differentiation of neural crest cells.

American journal of physiology. Cell physiology - 1 Aug 2011

Huang Wen-Yan, Xie Weibing, Guo Xia, Li Fengmin, Jose Pedro A, Chen Shi-You

Abstract excerpt

Response gene to complement 32 (RGC-32) is activated by transforming growth factor- β (TGF-β) and plays an important role in smooth muscle cell (SMC) differentiation from neural crest Monc-1 cells. The molecular mechanism governing TGF-β activation of RGC-32, however, remains to be determined. The present studies indicate that TGF-β regulates RGC-32 gene transcription. Sequence analysis revealed a Smad binding...

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Identifiers

PMID: 21613609
DOI: 10.1152/ajpcell.00480.2010
PMCID: PMC3154553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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