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Article

MicroRNA-31 is a positive modulator of endothelial-mesenchymal transition and associated secretory phenotype induced by TGF-β.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jan 2016

Katsura Akihiro, Suzuki Hiroshi I, Ueno Toshihide, Mihira Hajime, Yamazaki Tomoko, Yasuda Takahiko, Watabe Tetsuro, Mano Hiroyuki, Yamada Yoshitsugu, Miyazono Kohei

Abstract excerpt

Transforming growth factor-β (TGF-β) plays central roles in endothelial-mesenchymal transition (EndMT) involved in development and pathogenesis. Although EndMT and epithelial-mesenchymal transition are similar processes, roles of microRNAs in EndMT are largely unknown. Here, we report that constitutively active microRNA-31 (miR-31) is a positive regulator of TGF-β-induced EndMT. Although the expression is not...

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Identifiers

PMID: 26663584
DOI: 10.1111/gtc.12323

Genes

CCL17
CXCL16
TNF
VAV3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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