Article

FAM155B driven by BPTF promotes breast cancer progression and paclitaxel resistance via SREBP1-mediated fatty acid metabolic reprogramming

2026-07-21

Abstract excerpt

<title>Abstract</title> <p>Background Breast cancer poses a severe global public health burden, where tumor progression, metastasis and chemoresistance substantially compromise therapeutic outcomes. Metabolic reprogramming, particularly aberrant fatty acid metabolism, facilitates malignant transformation and drug resistance. Nevertheless, the key molecular mediators linking lipid remodeling to breast cancer adva...

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Literature Corpus work: c79353ef-4072-5ce7-be2b-b4c5ef10e68c
DOI: 10.21203/rs.3.rs-10340968/v1

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