Article

<i>Entropy Fusion DNA:</i> Alignment-Free Gene Fusion Detection through Entropy and Mutual Information Descriptors

2026-05-30

Abstract excerpt

<h4>ABSTRACT</h4> Gene fusions are clinically relevant genomic alterations and key cancer biomarkers. Their computational detection remains dominated by alignment-based pipelines, whose reliance on read mapping, reference annotations, and heuristic filtering makes them sensitive to mapping ambiguities, annotation incompleteness, repetitive regions, and false positives. Recent machine learning (ML) strategies aim...

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Literature Corpus work: c779fcb0-aa48-5d50-92c2-30078a230852
DOI: 10.64898/2026.05.27.728176

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