Article

Benchmarking Genomic Foundation Models for Gene Fusion Detection from DNA Sequences

2025-12-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Gene fusions are critical drivers of oncogenesis and diagnostic biomarkers in various cancers. However, their detection from RNA or DNA sequencing, when performed using traditional analytical methods, encounters challenges related to sample quality, computational complexity, and noise. Although deep learning is more robust, it usually requires large labeled da...

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Literature Corpus work: 585aacfb-4d49-543c-a1a2-fde999fa5ca5
DOI: 10.21203/rs.3.rs-8360344/v1

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