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Article

A cross-cohort computational framework to trace tumor tissue-of-origin based on RNA sequencing

2023-06-26

Abstract excerpt

Carcinoma of unknown primary (CUP) is a type of metastatic cancer with tissue-of-origin (TOO) unidentifiable by traditional methods. CUP patients typically have poor prognosis but therapy targeting the original cancer tissue can significantly improve patients’ prognosis. Thus, it’s critical to develop accurate computational methods to infer cancer TOO. While qPCR or microarray-based methods are effective in inferr...

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Literature Corpus work
c752ce30-a5d6-5a72-8f49-c4f2a1ad18d0
DOI
10.21203/rs.3.rs-3037313/v1
Open publication

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A cross-cohort computational framework to trace tumor tissue-of-origin based on RNA sequencingDOI 10.21203/rs.3.rs-3037313/v1
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