Article

A computational framework to trace tumor tissue-of-origin of 19 cancer types based on RNA sequencing

2022-03-18

Abstract excerpt

Carcinoma of unknown primary (CUP) is a type of metastatic cancer with tissue-of-origin (TOO) unidentifiable by traditional methods. Most CUP patients have poor prognosis since no therapy targeting TOO is allowed. Thus, it’s critical to develop accurate computational methods to infer TOO. While qPCR or microarray-based methods are effective in predicting TOO for most cancer types, the overall prediction accuracy i...

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Literature Corpus work: 6fd086d8-1c2e-510e-bf34-c88e82ad39b9
DOI: 10.21203/rs.3.rs-1457167/v1

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