Article

Non-Invasive classification of macrophage polarisation by 2P-FLIM and machine learning

2022-01-23

Abstract excerpt

1. In this study, fluorescence lifetime imaging of NAD(P)H-based cellular autofluorescence is applied as a non-invasive modality to classify two contrasting states of human macrophages by proxy of their governing metabolic state. Macrophages were obtained from human blood-circulating monocytes, polarised using established treatments, and metabolically challenged using small molecules to validate their responding m...

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Literature Corpus work: c74d37d7-6c26-5a3f-9b48-5e031bdf187f
DOI: 10.1101/2022.01.22.477332

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