Article
Phenotypic, Metabolic, and Functional Characterization of Experimental Models of Foamy Macrophages: Toward Therapeutic Research in Atherosclerosis.
International journal of molecular sciences - 21 Sept 2024
Henni Mansour Amina Sarah, Ragues Mathilde, Brevier Julien, Borowczyk Coraline, Grevelinger Janaïna, Laroche-Traineau Jeanny, Garaude Johan, Marais Sébastien, Jacobin-Valat Marie-Josée, Gerbaud Edouard, Clofent-Sanchez Gisèle, Ottones Florence
Abstract excerpt
Different types of macrophages (Mφ) are involved in atherogenesis, including inflammatory Mφ and foamy Mφ (FM). Our previous study demonstrated that two-photon excited fluorescence (TPEF) imaging of NADH and FAD autofluorescence (AF) could distinguish experimental models that mimic the different atherosclerotic Mφ types. The present study assessed whether optical differences correlated with phenotypic and...
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