Article

Autofluorescence imaging of 3D tumor-macrophage microscale cultures resolves spatial and temporal dynamics of macrophage metabolism

2020-03-12

Abstract excerpt

<h4>ABSTRACT</h4> Macrophages within the tumor microenvironment (TME) exhibit a spectrum of pro-tumor and anti-tumor functions, yet it is unclear how the TME regulates this macrophage heterogeneity. Standard methods to measure macrophage heterogeneity require destructive processing, limiting spatiotemporal studies of function within the live, intact 3D TME. Here, we demonstrate two-photon autofluorescence imaging...

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Literature Corpus work: 00c13c3e-a6be-5d5a-b36d-43d557360170
DOI: 10.1101/2020.03.12.989301

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