Article
Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy.
Journal of biomedical optics - 30 Apr 2016
Alfonso-García Alba, Smith Tim D, Datta Rupsa, Luu Thuy U, Gratton Enrico, Potma Eric O, Liu Wendy F
Abstract excerpt
Macrophages adopt a variety of phenotypes that are a reflection of the many functions they perform as part of the immune system. In particular, metabolism is a phenotypic trait that differs between classically activated, proinflammatory macrophages, and alternatively activated, prohealing macrophages. Inflammatory macrophages have a metabolism based on glycolysis while alternatively activated macrophages...
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